TNF RI Recombinant Protein

• Background:

  Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) is a member of the tumor necrosis factor receptor superfamily. TNFRSF1A is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome.

• NCBI Gene ID:

  7132

• Swiss Prot:

  P19438

• Accession Number:

  P19438

• Tag:

  C-Fc tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Immunology, Signal Transduction, Other, Inflammasomes

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  47.2 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Tumor necrosis factor receptor superfamily member 1A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Tumor necrosis factor receptor superfamily member 1A, TNFRSF1A, Tumor necrosis factor receptor 1, TNF-R1, TNF-RI, p55, p60, CD120a, TNFAR, TNFR1, TNFRSF1A

• Species:

  Human

• Protein ID:

  767974353

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3