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TNF beta Recombinant Protein

CAT: 0223-91-161Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-161Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tumor Necrosis Factor beta (TNF- beta) is a secreted protein belonging to the tumor necrosis factor family. TNF- beta binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds to TNFRSF3/LTBR in heterotrimeric form with LTB. TNF- beta forms heterotrimers with lymphotoxin-beta, which anchors TNF- beta to the cell surface. TNF- beta mediates the inflammatory, immunostimulatory, and antiviral response, involves in the formation of second lymphoid organs during development, has a role in apoptosis. TNF- beta is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.
CAS Number
9000-83-3
NCBI Gene ID
4049
Swiss Prot
P01374
Accession Number
P01374
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Immunology, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
18.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Lymphotoxin alpha
NCBI Organism
Homo sapiens
Other Product Names
Lymphotoxin-Alpha, LT-Alpha, TNF-Beta, Tumor Necrosis Factor Ligand Superfamily Member 1, LTA, TNFB, TNFSF1, TNFSF1B
Species
Human
Physical Properties
Lyophilized

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