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IGF-BP3 Recombinant Protein

CAT: 0223-40-153-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0223-40-153-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IGF-BP3 is a 30 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals and it is also found in α -granules of platelets. In addition to its ability to modulate the activity of IGF-I and IGF-II, IGF-BP3 exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues.
NCBI Gene ID
3486
Swiss Prot
P17936
Accession Number
NP_000589.2
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Cell Cycle, Growth Factors, Homeostasis, Obesity, Signal Transduction, Stem Cell
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized IGF-BP3 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IGF-BP3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IGF-BP3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Insulin-like growth factor binding protein 3
NCBI Organism
Homo sapiens
Other Product Names
IBP3, BP-53, IBP3, Insulin-like growth factor-binding protein 3, IBP-3
Species
Human
Protein ID
62243068
Physical Properties
Lyophilized

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