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TIMP-1 Recombinant Protein

CAT: 0223-40-141-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0223-40-141-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TIMP1 is an extracellular inhibitor of MMPs (see above) including MMP1, 2, 3, 7, 8, 9, 10, 11, 12, 13, and 16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors. Recombinant human TIMP-1 is a 20.6 kDa protein containing 184 amino acid residues.
NCBI Gene ID
7076
Swiss Prot
P01033
Accession Number
NP_003245.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Cell Cycle, Signal Transduction
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized TIMP-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TIMP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TIMP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
TIMP metallopeptidase inhibitor 1
NCBI Organism
Homo sapiens
Other Product Names
EPA, EPO, HCI, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA
Species
Human
Protein ID
4507509
Physical Properties
Lyophilized