Products for Research Use Only
RegisterLogin

CD107a Antibody [H4A3]

CAT: 0223-99-598Size: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-99-598Size:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by activated T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium, and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.
NCBI Gene ID
3916
Swiss Prot
P11279
Accession Number
P11279
Host
Mouse
Reactivity
Human, Rhesus Monkey, African Green Monkey, Pigtail Macaque, Sooty Mangabey
Immunogen
Human adherent peripheral blood cells
Clonality
Monoclonal
Clone
[H4A3]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Concentration
0.1 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG1
Specificity
CD107a
Applications Notes
CD107a Antibody [H4A3] for use in flow cytometry, immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, immunoprecipitation, and purification assays.
Symbol
LAMP1
NCBI Official Name
Lysosomal-associated membrane protein 1
NCBI Organism
Homo sapiens
Other Product Names
LAMP-1, lysosome-associated membrane protein 1
Tested Applications
Flow
Physical Properties
Liquid

Related Products

CatalogName
99-109CD107a Antibody [1D4B]
99-110CD107a Antibody [1D4B] (FITC)
99-111CD107a Antibody [1D4B] (APC)
99-603CD107b Antibody [H4B4]
99-606CD107b Antibody [H4B4] (PE)
99-112CD107b Antibody [ABL-93]
99-605CD107b Antibody [H4B4] (Biotin)
99-604CD107b Antibody [H4B4] (FITC)
36-216CD137 Antibody
14-353CD127 Antibody

Alternative Products

CatalogName
APR08123GMonoclonal LAMP1 / CD107a Antibody (clone H4A3), Clone: H4A3
E-AB-F1149A-01Purified Anti-Human CD107a Antibody[H4A3]
F488-30046-01FineTest®488 Anti-Human CD107a Antibody (H4A3)
F700-30046-01FineTest®700 Anti-Human CD107a Antibody (H4A3)
FCE2987-01PE Anti-Human CD107a/LAMP-1 Antibody[H4A3]
NBP2-25183APCMouse Monoclonal LAMP-1/CD107a Antibody (H4A3) [Allophycocyanin]
NBP2-25183PEMouse Monoclonal LAMP-1/CD107a Antibody (H4A3) [PE]
FCE2986-01FITC Anti-Human CD107a/LAMP-1 Antibody[H4A3]
MBS2569709-01AF488 Anti-Human CD107a/LAMP-1 Antibody [H4A3]
PE5-30046-01PE-FineTest®594 Anti-Human CD107a Antibody (H4A3)

Popular Products