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CD137 Antibody

CAT: 0223-36-216Size: 100 µgDry Ice: NoHazardous: No
CAT#:0223-36-216Size:100 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD137 is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.
NCBI Gene ID
3604
Swiss Prot
Q07011
Accession Number
728738
Host
Rabbit
Reactivity
Human
Immunogen
Human CD137.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Concentration
1 mg/ml
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Specificity
Recognizes human CD137. Detects a band of ~29kDa by Western blot. Does not cross-react with mouse CD137.
Applications Notes
Flow Cytometry: (1:500-1:1,000) . Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 with 5% skim milk. Suggested incubation time is 1 hour at room temperature) . Optimal conditions must be determined individually for each application.
Symbol
TNFRSF9
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 9
NCBI Organism
Homo sapiens
Other Product Names
4-1BB; TNFRSF9
Tested Applications
Flow, WB
Protein ID
Q07011
Physical Properties
Liquid

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