CD22 Antibody [2D6]

CAT: 0223-98-676Size: 0.5 mgDry Ice: NoHazardous: No
CAT#:0223-98-676Size:0.5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface concomitant with IgD, and is found on most IgM+IgD+ mature B lymphocytes. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via cross-linking of surface Ig increases CD22 expression. CD22 associates with the B cell receptor (BCR) complex and mediates intercellular adhesion. Its intracellular domain is phosphorylated after antigen receptor cross-linking and is involved in negative regulation of B cell activation.
NCBI Gene ID
12483
Swiss Prot
P35329
Accession Number
P35329
Host
Rat
Reactivity
Mouse
Immunogen
Splenic lymphocyte plasma membranes from CBA x C57 F1 mice
Clonality
Monoclonal
Clone
[2D6]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Stem Cell, Immunology
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG1
Specificity
CD22
Applications Notes
CD22 Antibody [2D6] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and activation assays.
Symbol
Cd22
NCBI Official Name
CD22 antigen
NCBI Organism
Mus musculus
Other Product Names
Lyb-8, Leu-14, BL-CAM
Tested Applications
ELISA, WB, IHC-P, Flow, IP
Physical Properties
Liquid

Related Products

CatalogName
RF16036-01PDL1 Antibody [2D6]
RF16036-002mgPDL1 Antibody [2D6]
RF16036-01mgPDL1 Antibody [2D6]
79-684CD22 Antibody
38-113CD22 Antibody
33-491CD22 Antibody [FR10B4]
38-114CD22 Antibody (biotin)
33-492CD22 Antibody [MYG13]
40-147-002mgCD22 Recombinant Protein
40-147-01CD22 Recombinant Protein

Alternative Products

CatalogName
AM08033FC-NCd22 Rat Monoclonal Antibody [Clone ID: 2D6]
APG02819GMonoclonal CTH Antibody (clone 2D6), Clone: 2D6
MBS154573-01PDL1 Antibody [2D6]
MBS8517032-01CD22 Antibody
sc-56313GW182 (2D6)

Popular Products