TAL-1 (phospho Ser122) Antibody

• Background:

  TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

• NCBI Gene ID:

  6886

• Swiss Prot:

  P17542

• Accession Number:

  NP_001274276.1

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  TAL-1 (phospho Ser122) antibody was raised against a peptide sequence around phosphorylation site of Serine 122 (Q-L-S (p) -P-P) derived from Human TAL-1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  IgG

• Specificity:

  The antibody detects endogenous levels of TAL-1 only when phosphorylated at serine 122.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  TAL1

• NCBI Official Name:

  T-cell acute lymphocytic leukemia 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Aplan P.D., Mol. Cell. Biol. 10:6426-6435 (1990) .

• Background Reference 02:

  Gregory S.G., Nature 441:315-321 (2006) .

• Background Reference 03:

  Chen Q., J. Exp. Med. 172:1403-1408 (1990) .

• Other Product Names:

  SCL, TAL1, TCL5

• Tested Applications:

  WB

• Protein ID:

  4507363

• Physical Properties:

  Liquid