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IKK-γ (phospho Ser376) Antibody

CAT: 0223-79-846Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-846Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males. In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation.
NCBI Gene ID
8517
Swiss Prot
Q9Y6K9
Accession Number
NP_001093327.1
Host
Rabbit
Reactivity
Human
Immunogen
IKK-γ (phospho Ser376) antibody was raised against a peptide sequence around phosphorylation site of Serine 376 (Y-L-S (p) -S-P) derived from Human IKK-γ.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
48 kDa
Fragment
IgG
Specificity
The antibody detects endogenous levels of IKK-γ only when phosphorylated at serine 376.
Symbol
IKBKG
NCBI Official Name
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
NCBI Organism
Homo sapiens
Background Reference 01
Li Y., Proc. Natl. Acad. Sci. U.S.A. 96:1042-1047 (1999) .
Background Reference 02
Jin D.-Y., J. Biomed. Sci. 6:115-120 (1999) .
Background Reference 03
Rothwarf D.M., Nature 395:297-300 (1998) .
Other Product Names
FIP3, IKBKG, IKKAP1, IKKG, NF-kappaB
Tested Applications
IHC
Protein ID
3641279
Physical Properties
Liquid

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