Products for Research Use Only
RegisterLogin

IKK-γ (phospho Ser85) Antibody

CAT: 0223-79-979Size: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-79-979Size:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.
NCBI Gene ID
8517
Swiss Prot
Q9Y6K9
Accession Number
NP_001093326.2
Host
Rabbit
Reactivity
Human
Immunogen
IKK-γ (phospho Ser85) antibody was raised against a peptide sequence around phosphorylation site of serine 85 (Q-A-S (p) -Q-R) derived from Human IKK-gamma.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
48 kDa
Fragment
IgG
Specificity
The antibody detects endogenous level of IKK-γ only when phosphorylated at serine 85.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
IKBKG
NCBI Official Name
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
NCBI Organism
Homo sapiens
Background Reference 01
Niu J, Shi Y, Iwai K, Wu ZH (2011) EMBO J 30, 3741-53. Wu ZH, et al. (2010) Mol Cell 40, 75-86. Palkowitsch L, Leidner J, Ghosh S, Marienfeld RB (2008) J Biol Chem 283, 76-86.
Other Product Names
FIP-3, FIP3, I-kappa-B kinase gamma, IKK-gamma, IKKAP1
Tested Applications
WB
Protein ID
3641279
Physical Properties
Liquid

Related Products

CatalogName
79-161IKK a (phospho Thr23) Antibody
79-846IKK-γ (phospho Ser376) Antibody
79-980IKK- beta (phospho Tyr188) Antibody
79-982IKK- alpha/ beta (phospho Ser176/177) Antibody
2115-002mgIKK alpha Antibody
2121-01IKK beta Antibody
2117-01IKK alpha Antibody
2121-01mgIKK beta Antibody
2329-002mgIKK epsilon Antibody
2025-002mgIKK alpha Antibody

Alternative Products

CatalogName
E18-3496-2Phospho-IKK-γ (Ser85) Antibody
8A1151-AATIKK-γ (Phospho-Ser85) Antibody
A1151-01IKKγ (phospho Ser85) Antibody
E44H00924IKKγ (phospho Ser85) Polyclonal Antibody
AF3496-01Phospho-IKK gamma (Ser85) Antibody
MBS855729-01IKK-gamma (Phospho-Ser85) Antibody
MBS8511677-01Phospho-IKK-gamma (Ser85) Antibody
AF5431-BPPhospho-IKK gamma (Ser85) Peptide
ES7801-01IKKγ (phospho Ser85) rabbit pAb
JOT-AP02163-01IKK gamma(Phospho Ser85) Polyclonal Antibody

Popular Products