LGR5 Antibody

• Background:

  Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.

• NCBI Gene ID:

  8549

• Swiss Prot:

  O75473

• Accession Number:

  NP_003658.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  LGR5 (GPR49) antibody was raised against a peptide sequence around aa.490~494 (K-I-S-N-Q) derived from Human LGR5 (GPR49) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  95 kDa

• Specificity:

  This antibody detects endogenous level of total LGR5 (GPR49) protein.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  LGR5

• NCBI Official Name:

  Leucine-rich repeat containing G protein-coupled receptor 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yamamoto Y., Sakamoto M., Fujii G., Tsuiji H., Kenetaka K., Asaka M., Hirohashi S. Hepatology 37:528-533 (2003) McClanahan T., Koseoglu S., Smith K., Grein J., Gustafson E., Black S., Kirschmeier P., Samatar A. A. Cancer Biol. Ther. 5:419-426 (2006) Becker L., Huang Q., Mashimo H. Scientific World Journal 8:1168-1176 (2008)

• Other Product Names:

  FEX, HG38, GPR49, GPR67, GRP49, PRKCT, FEX, MGC117008

• Tested Applications:

  WB

• Protein ID:

  4504379

• Physical Properties:

  Liquid