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PPARgamma Antibody

CAT: 0223-79-749Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-749Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis.
NCBI Gene ID
5468
Swiss Prot
P37231
Accession Number
NP_005028.4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
PPARgamma antibody was raised against a peptide sequence around aa.50~54 (L-S-V-M-E) derived from Human PPARγ .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
53 57 kDa
Specificity
This antibody detects endogenous levels of total PPARγ protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
PPARG
NCBI Official Name
Peroxisome proliferator-activated receptor gamma
NCBI Organism
Homo sapiens
Background Reference 01
"Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARgamma2 versus PPARgamma1 and activation with retinoid X receptor agonists and antagonists. "Mukherjee R., Jow L., Croston G. E., et al. J. Biol. Chem. 272:8071-8076 (1997) "Cloning and characterization of RAP250, a nuclear receptor coactivator. "Caira F., Antonson P., Pelto-Huikko M., et al. J. Biol. Chem. 275:5308-5317 (2000) "Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha. "Qi C., Chang J., Zhu Y., et al. J. Biol. Chem. 277:28624-28630 (2002)
Other Product Names
GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma, MAPTL, MTBT1, TAU, GLM1, PPARG
Tested Applications
WB
Protein ID
116284368
Physical Properties
Liquid

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