Notch1 Antibody [mN1A] (PE)

• Background:

  The mN1A monoclonal antibody reacts with the intracellular domain of human and mouse Notch1 with high affinity for the activated intracellular form and lower affinity for the full length heterodimeric Notch1 forms. It does not react with Notch2,3, or 4 and does not cross-react with rat thymocytes. The neurogenic locus homolog protein 1 (Notch1) is a trasmembrane receptor that regulates cell fate decisions. It is expressed in CD4-CD8- and CD4-CD8+ thymocytes, and plays a role in the regulation of myelopoiesis and lymphopoiesis.

• NCBI Gene ID:

  4851;18128

• Swiss Prot:

  P46531; Q01705

• Host:

  Mouse

• Reactivity:

  Human, Mouse

• Clonality:

  Monoclonal

• Clone:

  MN1A

• Conjugation:

  PE

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell, Cell Cycle

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

• Fragment:

  Mouse IgG1, kappa

• Specificity:

  The mN1A monoclonal antibody reacts with the intracellular domain of human and mouse Notch1 with high affinity for the activated intracellular form and lower affinity for the full length heterodimeric Notch1 forms.

• Symbol:

  NOTCH1

• NCBI Official Name:

  Notch 1

• NCBI Organism:

  Homo sapiens; Mus musculus

• Other Product Names:

  HN1, AOS5, TAN1, AOVD1, NOTCH1

• Tested Applications:

  Flow

• Physical Properties:

  Liquid