CD10 Antibody [CB-CALLA] (APC)

• Background:

  The CB-CALLA monoclonal antibody specifically reacts with human CD10, a 100kDA type II glycoprotein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on neutrophils and the precursors of B and T cells. It is involved in the neutrophil inflammatory and chemotactic responses and B cell development.

• NCBI Gene ID:

  4311

• Swiss Prot:

  P08473

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Clone:

  CB-CALLA

• Conjugation:

  APC

• Type:

  Primary Antibodies

• Field of Research:

  Innate Immunity

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

• Fragment:

  Mouse IgG2b, kappa

• Specificity:

  The CB-CALLA monoclonal antibody specifically reacts with human CD10, a 100kDA type II glycoprotein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin.

• Symbol:

  MME

• NCBI Official Name:

  Membrane metallo-endopeptidase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

• Background Reference 02:

  Ritz, J., Pesando, J. M., Notis-McConarty, J., Lazarus, H., Schlossman, S. F. (1980) . A monoclonal antibody to human acute lymphoblastic leukaemia antigen.

• Background Reference 03:

  McCormack, R. T., Nelson, R. D., LeBien, T. W. (1986) . Structure/function studies of the common acute lymphoblastic leukemia antigen (CALLA/CD10) expressed on human neutrophils.The Journal of Immunology,137 (3), 1075-1082.

• Other Product Names:

  NEP, SFE, CD10, CALLA, MME

• Tested Applications:

  Flow

• Physical Properties:

  Liquid