CD10 Antibody [2A1H5E1]

• Background:

  CD10 is a 100 kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA) . It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML) . It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

• NCBI Gene ID:

  4311

• Swiss Prot:

  P08473

• Accession Number:

  P08473

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Ni-NTA purified recombinant human CD-10 expressed in E. Coli strain BL21 (DE3) .

• Clonality:

  Monoclonal

• Clone:

  2A1H5E1

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Antibody is purified by protein G affinity chromatography.

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody in PBS containing 0.03% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  CD10 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG2b

• Symbol:

  MME

• NCBI Official Name:

  Membrane metallo-endopeptidase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sato Y, et.al. Journal of Gastroenterology,1996 Feb.31 (1) :12-7.

• Background Reference 02:

  Inukai T, et.al. British Journal of Haematology,1995,89 (3) :623-6.

• Other Product Names:

  EPN, Atriopeptidase, CALLA, NEP, SFE, CD10

• Tested Applications:

  ELISA, IHC

• Protein ID:

  128062