SH3GL1 Antibody

• Background:

  SH3GL1 may play a regulatory role in synaptic vesicle recycling. It interacts with SYNJ1 and DNM1 through its SH3 domain with the proline-rich region of mixed lineage Leukemia (MLL) in either the fusion or the normal MLL protein. This protein is located in cytoplasmic, and peripheral membrane protein associated with internal membranes. Concentrated in presynaptic nerve terminals in neurons (By similarity) . It’s expressed ubiquitously. Higher expression in pancreas, placenta, prostate, testis and uterus. In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.

• NCBI Gene ID:

  6455

• Swiss Prot:

  Q99961

• Accession Number:

  NP_003016.1

• Host:

  Chicken

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  1-360

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  Immunoaffinity Purified

• Concentration:

  1 mg/mL

• Buffer:

  Phosphate-Buffered Saline. No preservatives added.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  SH3GL1 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39.8 kDa (calculated)

• Applications Notes:

  SH3-containing Grb-2-like 1 protein antibody can be used for the detection of SH3-containing Grb-2-like 1 protein by Western Blot.

• Symbol:

  SH3GL1

• NCBI Official Name:

  SH3-domain GRB2-like 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CNSA1, SH3D2B, Endophilin-A2, EEN fusion partner of MLL, EEN, CNSA1, SH3P8, SH3containing Grb2like 1 protein

• Tested Applications:

  WB

• Protein ID:

  4506929

• Physical Properties:

  Liquid