DAZAP2 Antibody

• Background :

  DAZAP2 encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma.

• NCBI Gene ID :

  9802

• Swiss Prot :

  Q15038

• Accession Number :

  Q15038

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This DAZAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the C-terminal region of human DAZAP2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  17 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  DAZAP2

• NCBI Official Name :

  DAZ-associated protein 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

• Background Reference 02 :

  Kim, J.E., et al. Mol. Cell. Biol. 28 (2) :803-813 (2008)

• Background Reference 03 :

  Shi, Y.W., et al. Chin. Med. J. 120 (19) :1659-1665 (2007)

• Other Product Names :

  DAZ-associated protein 2, Deleted in azoospermia-associated protein 2, DAZAP2, KIAA0058

• Tested Applications :

  WB, IHC-P

• Protein ID :

  44887865

• Physical Properties :

  Liquid