POLL Antibody

• Background :

  This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes.

• NCBI Gene ID :

  27343

• Swiss Prot :

  Q9UGP5

• Accession Number :

  Q9UGP5

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This POLL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-575 amino acids from the C-terminal region of human POLL.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  63 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  POLL

• NCBI Official Name :

  DNA polymerase lambda

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Brown, J.A., et al. J. Mol. Biol. 395 (2) :282-290 (2010)

• Background Reference 02 :

  Van Loon, B., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (43) :18201-18206 (2009)

• Background Reference 03 :

  Garcia-Diaz, M., et al. Nat. Struct. Mol. Biol. 16 (9) :967-972 (2009)

• Other Product Names :

  DNA polymerase lambda, Pol Lambda, 4299-, DNA polymerase beta-2, Pol beta2, DNA polymerase kappa, POLL

• Tested Applications :

  WB

• Protein ID :

  17367126

• Physical Properties :

  Liquid