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HCCS Antibody

CAT: 0223-64-165Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-165Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7) . Three transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
3052
Swiss Prot
P53701
Accession Number
P53701
Host
Rabbit
Reactivity
Human
Immunogen
This HCCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-200 amino acids from the Central region of human HCCS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Symbol
HCCS
NCBI Official Name
Cytochrome c-type heme lyase
NCBI Organism
Homo sapiens
Background Reference 01
Need, A.C., et al. Hum. Mol. Genet. 18 (23) :4650-4661 (2009)
Background Reference 02
Wimplinger, I., et al. Mol. Vis. 13, 1475-1482 (2007)
Background Reference 03
Wimplinger, I., et al. Am. J. Hum. Genet. 79 (5) :878-889 (2006)
Background Reference 04
Nakashima-Kamimura, N., et al. J. Cell. Sci. 118 (PT 22), 5357-5367 (2005)
Other Product Names
Cytochrome c-type heme lyase, CCHL, Holocytochrome c-type synthase, HCCS, CCHL
Tested Applications
WB, IHC-P
Protein ID
1705694
Physical Properties
Liquid

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