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MMAA Antibody

CAT: 0223-64-120Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-120Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria.
NCBI Gene ID
166785
Swiss Prot
Q8IVH4
Accession Number
Q8IVH4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MMAA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human MMAA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Symbol
MMAA
NCBI Official Name
Methylmalonic aciduria type A protein, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Honjo, R.S., et al. Genet Test Mol Biomarkers 13 (2) :181-183 (2009)
Background Reference 02
Merinero, B., et al. J. Inherit. Metab. Dis. 31 (1) :55-66 (2008)
Background Reference 03
Horster, F., et al. Pediatr. Res. 62 (2) :225-230 (2007)
Background Reference 04
Padovani, D., et al. J. Biol. Chem. 281 (26) :17838-17844 (2006)
Other Product Names
Methylmalonic aciduria type A protein, mitochondrial, 36--, MMAA
Tested Applications
WB, IHC-P
Protein ID
38258173
Physical Properties
Liquid

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