PIGN Antibody

• Background:

  PIGN is involved in glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor.

• NCBI Gene ID:

  23556

• Swiss Prot:

  O95427

• Accession Number:

  O95427

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PIGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-235 amino acids from the N-terminal region of human PIGN.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  106 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PIGN

• NCBI Official Name:

  GPI ethanolamine phosphate transferase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  McDonough, C.W., et al. Hum. Genet. (2009) In press :

• Background Reference 02:

  Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)

• Background Reference 03:

  Kinoshita, T., et al. Curr Opin Chem Biol 4 (6) :632-638 (2000)

• Background Reference 04:

  Hong, Y., et al. J. Biol. Chem. 274 (49) :35099-35106 (1999)

• Other Product Names:

  GPI ethanolamine phosphate transferase 1, 2---, MCD4 homolog, Phosphatidylinositol-glycan biosynthesis class N protein, PIG-N, PIGN, MCD4

• Tested Applications:

  WB

• Physical Properties:

  Liquid