PIGS Antibody

• Background:

  This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq].

• NCBI Gene ID:

  94005

• Swiss Prot:

  Q96S52

• Accession Number:

  Q96S52

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PIGS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-555 amino acids from the C-terminal region of human PIGS.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  62 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PIGS

• NCBI Official Name:

  GPI transamidase component PIG-S

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Vainauskas, S., et al. J. Biol. Chem. 280 (16) :16402-16409 (2005)

• Background Reference 02:

  Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)

• Background Reference 03:

  Hong, Y., et al. Mol. Biol. Cell 14 (5) :1780-1789 (2003)

• Background Reference 04:

  Ohishi, K., et al. J. Biol. Chem. 278 (16) :13959-13967 (2003)

• Other Product Names:

  GPI transamidase component PIG-S, Phosphatidylinositol-glycan biosynthesis class S protein, PIGS

• Tested Applications:

  WB

• Protein ID:

  21759353

• Physical Properties:

  Liquid