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PIGO Antibody

CAT: 0223-59-078Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-078Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least two alternatively spliced transcripts encoding distinct isoforms have been found for this gene.
NCBI Gene ID
84720
Swiss Prot
Q8TEQ8
Accession Number
Q8TEQ8
Host
Rabbit
Reactivity
Human
Immunogen
This PIGO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 955-983 amino acids from the C-terminal region of human PIGO.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
119 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PIGO
NCBI Official Name
GPI ethanolamine phosphate transferase 3
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 04
Humphray, S.J., et al. Nature 429 (6990) :369-374 (2004)
Other Product Names
GPI ethanolamine phosphate transferase 3, 2---, Phosphatidylinositol-glycan biosynthesis class O protein, PIG-O, PIGO
Tested Applications
WB
Protein ID
61252289
Physical Properties
Liquid

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