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HFE2 Antibody

CAT: 0223-64-070Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-070Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HFE2 is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin.
NCBI Gene ID
148738
Swiss Prot
Q6ZVN8
Accession Number
Q6ZVN8
Host
Rabbit
Reactivity
Human
Immunogen
This HFE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-162 amino acids from the Central region of human HFE2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Symbol
HFE2
NCBI Official Name
Hemojuvelin
NCBI Organism
Homo sapiens
Background Reference 01
Zhu, X., et al. Genet. Epidemiol. 34 (2) :171-187 (2010)
Background Reference 02
Barton, J.C., et al. Am. J. Hematol. 84 (11) :710-714 (2009)
Background Reference 03
Zhang, A.S., et al. J. Biol. Chem. 284 (34) :22580-22589 (2009)
Other Product Names
Hemojuvelin, Hemochromatosis type 2 protein, RGM domain family member C, HFE2, HJV, RGMC
Tested Applications
WB, IHC-P
Protein ID
51316254
Physical Properties
Liquid

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