GBE1 Antibody

• Background :

  GBE1 is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease) .

• NCBI Gene ID :

  2632

• Swiss Prot :

  Q04446

• Accession Number :

  Q04446

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This GBE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the Central region of human GBE1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  80 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  GBE1

• NCBI Official Name :

  1,4-alpha-glucan-branching enzyme

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Konstantinidou, A.E., et al. Placenta 29 (4) :378-381 (2008)

• Background Reference 02 :

  Massa, R., et al. Muscle Nerve 37 (4) :530-536 (2008)

• Background Reference 03 :

  Bruno, C., et al. Acta Myol 26 (1) :75-78 (2007)

• Other Product Names :

  4-alpha-glucan-branching enzyme, Brancher enzyme, Glycogen-branching enzyme, GBE1

• Tested Applications :

  WB, IF

• Protein ID :

  357529509

• Physical Properties :

  Liquid