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GABRA2 Antibody

CAT: 0223-63-879Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-879Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GABRA2 is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
NCBI Gene ID
2555
Swiss Prot
P47869
Accession Number
P47869
Host
Rabbit
Reactivity
Human
Immunogen
This GABRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the C-terminal region of human GABRA2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
GABRA2
NCBI Official Name
Gamma-aminobutyric acid receptor subunit alpha-2
NCBI Organism
Homo sapiens
Background Reference 01
Das, S., et.al., Stat Med 29 (11), 1250-1258 (2010)
Background Reference 02
Bierut, L.J., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (11), 5082-5087 (2010)
Background Reference 03
Dixon, C.I., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (5), 2289-2294 (2010)
Other Product Names
Gamma-aminobutyric acid receptor subunit alpha-2, GABA (A) receptor subunit alpha-2, GABRA2
Tested Applications
WB, IHC-P, Flow
Protein ID
126302547
Physical Properties
Liquid

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