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GABRA4 Antibody

CAT: 0223-56-576Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-576Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
NCBI Gene ID
2557
Swiss Prot
P48169
Accession Number
P48169
Host
Rabbit
Reactivity
Human
Immunogen
This GABRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 amino acids from the Central region of human GABRA4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
62 kDa
Fragment
Rabbit Ig
Symbol
GABRA4
NCBI Official Name
Gamma-aminobutyric acid receptor subunit alpha-4
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 02
Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)
Background Reference 03
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 04
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Other Product Names
Gamma-aminobutyric acid receptor subunit alpha-4, GABA (A) receptor subunit alpha-4, GABRA4
Tested Applications
WB, Flow
Protein ID
206729865
Physical Properties
Liquid

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