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GABRA5 Antibody

CAT: 0223-25-239Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-25-239Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
2558
Swiss Prot
P31644
Accession Number
NP_000801
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRA5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GABRA5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
49 kDa
Applications Notes
GABRA5 antibody can be used for detection of GABRA5 by ELISA at 1:312500. GABRA5 antibody can be used for detection of GABRA5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GABRA5
NCBI Official Name
Gamma-aminobutyric acid (GABA) A receptor, alpha 5
NCBI Organism
Homo sapiens
Background Reference 01
Netzer, C., (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet. 147 (1), 37-41.
Other Product Names
GABRA5, MGC138184
Tested Applications
ELISA, WB
Protein ID
4503861
Physical Properties
Liquid

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