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GABRG2 Antibody

CAT: 0223-27-228Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-228Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GABRG2 is a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
NCBI Gene ID
2566
Swiss Prot
P18507
Accession Number
NP_000807
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRG2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GABRG2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
50 kDa
Applications Notes
GABRG2 antibody can be used for detection of GABRG2 by ELISA at 1:312500. GABRG2 antibody can be used for detection of GABRG2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GABRG2
NCBI Official Name
Gamma-aminobutyric acid (GABA) A receptor, gamma 2
NCBI Organism
Homo sapiens
Background Reference 01
Selmer, K.K., (2008) Acta Neurol. Scand. 117 (4), 289-292.
Other Product Names
GABRG2, CAE2, ECA2, GEFSP3
Tested Applications
ELISA, WB
Protein ID
38788135
Physical Properties
Liquid

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