RECK Antibody

• Background:

  RECK is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.

• NCBI Gene ID:

  8434

• Swiss Prot:

  O95980

• Accession Number:

  O95980

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RECK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-456 amino acids from the Central region of human RECK.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  106 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RECK

• NCBI Official Name:

  Reversion-inducing cysteine-rich protein with Kazal motifs

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Du, Y.Y., et.al., World J. Gastroenterol. 16 (7), 904-908 (2010)

• Background Reference 02:

  Pesta, M., et.al., Anticancer Res. 29 (11), 4535-4539 (2009)

• Background Reference 03:

  Takahashi, C., et.al., Tanpakushitsu Kakusan Koso 54 (13), 1742-1746 (2009)

• Other Product Names:

  Reversion-inducing cysteine-rich protein with Kazal motifs, hRECK, Suppressor of tumorigenicity 15 protein, RECK, ST15

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid