TPH2 Antibody

• Background:

  This protein is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.

• NCBI Gene ID:

  121278

• Swiss Prot:

  Q8IWU9

• Accession Number:

  Q8IWU9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-193 amino acids from the Central region of human TPH2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  56 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TPH2

• NCBI Official Name:

  Tryptophan 5-hydroxylase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Khatua, A.K., et.al., Virology 400 (1), 68-75 (2010)

• Background Reference 02:

  Koning, F.A., et.al., J. Virol. 83 (18), 9474-9485 (2009)

• Other Product Names:

  Tryptophan 5-hydroxylase 2, Neuronal tryptophan hydroxylase, Tryptophan 5-monooxygenase 2, TPH2, NTPH

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  30580625

• Physical Properties:

  Liquid