TPH1 Antibody

• Background :

  TPH1 is a member of the aromatic amino acid hydroxylase family. This protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter.

• NCBI Gene ID :

  7166

• Swiss Prot :

  P17752

• Accession Number :

  P17752

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This TPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human TPH1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Obesity, Neuroscience, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Chicken, Rabbit, Rat, Xenopus

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  51 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  TPH1

• NCBI Official Name :

  Tryptophan 5-hydroxylase 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Johansson, T.A., et.al., BMC Cancer 9, 321 (2009)

• Background Reference 02 :

  Kuhn, D.M., et.al., J. Neurochem. 68 (5), 2220-2223 (1997)

• Other Product Names :

  Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, TPH1, TPH, TPRH, TRPH

• Tested Applications :

  WB, IHC-P, IF, Flow

• Protein ID :

  116242823

• Physical Properties :

  Liquid