CDC2L6 Antibody

• Background:

  CDC2L6 is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.

• NCBI Gene ID:

  23097

• Swiss Prot:

  Q9BWU1

• Accession Number:

  Q9BWU1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CDC2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-285 amino acids from the Central region of human CDC2L6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  57 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CDK19

• NCBI Official Name:

  Cyclin-dependent kinase 19

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Malumbres, M., et.al. Nat. Cell Biol. 11 (11), 1275-1276 (2009)

• Background Reference 02:

  Loyer, P., et.al., J. Biol. Chem. 283 (12), 7721-7732 (2008)

• Other Product Names:

  Cyclin-dependent kinase 19, CDC2-related protein kinase 6, Cell division cycle 2-like protein kinase 6, Cell division protein kinase 19, Cyclin-dependent kinase 11, Death-preventing kinase, CDK19, CDC2L6, CDK11, KIAA1028

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  60391917

• Physical Properties:

  Liquid