CDC37 Antibody

• Background:

  CDC37 is a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

• NCBI Gene ID:

  11140

• Swiss Prot:

  Q16543

• Accession Number:

  Q16543

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  This CDC37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the Central region of human CDC37.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  44 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CDC37

• NCBI Official Name:

  Hsp90 co-chaperone Cdc37

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Dai, K., et.al., J. Biol. Chem. 271 (36), 22030-22034 (1996)

• Background Reference 02:

  Lamphere, L., et.al., Oncogene 14 (16), 1999-2004 (1997)

• Other Product Names:

  Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37, Hsp90 co-chaperone Cdc37, N-terminally processed, CDC37, CDC37A

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  21542000

• Physical Properties:

  Liquid