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PTK6 Antibody

CAT: 0223-22-985Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-22-985Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
5753
Swiss Prot
Q13882
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 222-451 of human PTK6 (NP_005966.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 60kDa
Fragment
IgG
Symbol
PTK6
Positive Control 2
BT-474
Positive Control 3
MCF7
Positive Control 4
A-549
Positive Control 5
NIH/3T3
Positive Control 6
Mouse liver
NCBI Official Name
Protein tyrosine kinase 6
NCBI Organism
Homo sapiens
Other Product Names
BRK, Breast tumor kinaseBRK
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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