PTK6 Antibody

• Background:

  The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  5753

• Swiss Prot:

  Q13882

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 222-451 of human PTK6 (NP_005966.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  SW480

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 60kDa

• Fragment:

  IgG

• Symbol:

  PTK6

• Positive Control 2:

  BT-474

• Positive Control 3:

  MCF7

• Positive Control 4:

  A-549

• Positive Control 5:

  NIH/3T3

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Protein tyrosine kinase 6

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  BRK, Breast tumor kinaseBRK

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid