PP2A alpha Antibody

CAT: 0223-63-484Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-484Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PPP2CA/B represents the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
NCBI Gene ID
5515
Swiss Prot
P67775
Accession Number
P67775
Host
Rabbit
Reactivity
Human
Immunogen
This PP2A alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-304 amino acids from the C-terminal region of human PP2A alpha.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Pig, Rabbit, Rat, Drosophila
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Symbol
PPP2CA
NCBI Official Name
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
NCBI Organism
Homo sapiens
Background Reference 01
Gergs, U., et al., J. Biol. Chem. 279 (39) :40827-40834 (2004) .
Background Reference 02
Prickett, T.D., et al., J. Biol. Chem. 279 (37) :38912-38920 (2004) .
Background Reference 03
Scott, G.K., et al., EMBO J. 22 (23) :6234-6244 (2003) .
Background Reference 04
Rao, R.K., et al., Biochem. Biophys. Res. Commun. 293 (1) :610-616 (2002) .
Other Product Names
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, RP-C, PPP2CA
Tested Applications
WB, IHC-P
Protein ID
54038809
Physical Properties
Liquid

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