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YWHAB Antibody

CAT: 0223-63-435Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-435Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
YWHAB belongs to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.
NCBI Gene ID
7529
Swiss Prot
P31946
Accession Number
P31946
Host
Rabbit
Reactivity
Human
Immunogen
This YWHAB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human YWHAB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey, Mouse, Rat, Zebrafish
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Symbol
YWHAB
NCBI Official Name
14-3-3 protein beta/alpha
NCBI Organism
Homo sapiens
Background Reference 01
Komori, T., et al., Acta Neuropathol. 106 (1) :66-70 (2003) . Cavet, M.E., et al., J. Biol. Chem. 278 (20) :18376-18383 (2003) . Li, Y., et al., J. Biol. Chem. 278 (16) :13663-13671 (2003) . Shumway, S.D., et al., J. Biol. Chem. 278 (4) :2089-2092 (2003) . Parvaresch, S., et al., FEBS Lett. 532 (3) :357-362 (2002) .
Other Product Names
14-3-3 protein beta/alpha, Protein 1054, Protein kinase C inhibitor protein 1, KCIP-1, 14-3-3 protein beta/alpha, N-terminally processed, YWHAB
Tested Applications
WB, IHC-P, IF
Protein ID
1345590
Physical Properties
Liquid

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