YWHAZ Antibody

• Background:

  This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

• NCBI Gene ID:

  7534

• Swiss Prot:

  P63104

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human YWHAZ (NP_001129171.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 28kDa

• Fragment:

  IgG

• Symbol:

  YWHAZ

• Positive Control 2:

  HeLa

• Positive Control 3:

  A-549

• Positive Control 4:

  MCF7

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Mouse lung

• NCBI Official Name:

  Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  YWHAZ, KCIP-1, MGC111427, MGC126532, MGC138156, HEL4, YWHAD, HEL-S-3, 14-3-3-zeta

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid