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YWHAZ Antibody

CAT: 0223-30-349Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-30-349Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.
NCBI Gene ID
7534
Swiss Prot
P63104
Accession Number
NP_003397
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human YWHAZ.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store YWHAZ antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
28 kDa, 28 kDa
Applications Notes
YWHAZ antibody can be used for detection of YWHAZ by ELISA at 1:62500. YWHAZ antibody can be used for detection of YWHAZ by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
YWHAZ
NCBI Official Name
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
NCBI Organism
Homo sapiens
Background Reference 01
Coblitz, B., (2005) J. Biol. Chem. 280 (43), 36263-36272.
Other Product Names
YWHAZ, KCIP-1, MGC111427, MGC126532, MGC138156, HEL4, YWHAD, HEL-S-3, 14-3-3-zeta
Tested Applications
ELISA, WB
Protein ID
4507953
Physical Properties
Liquid

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