Products for Research Use Only
RegisterLogin

YWHAZ Antibody

CAT: 0223-63-430Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-63-430Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.
NCBI Gene ID
7534
Swiss Prot
P63104
Accession Number
P63104
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This YWHAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-93 amino acids from the Central region of human YWHAZ.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Symbol
YWHAZ
NCBI Official Name
14-3-3 protein zeta/delta
NCBI Organism
Homo sapiens
Background Reference 01
Powell, D.W., et al., Mol. Cell. Biol. 23 (15) :5376-5387 (2003) .
Background Reference 02
Zhu, P., et al., Biochem. Biophys. Res. Commun. 301 (4) :991-999 (2003) .
Background Reference 03
Li, Y., et al., J. Biol. Chem. 277 (47) :44593-44596 (2002) .
Background Reference 04
Wang, H., et al., J. Clin. Endocrinol. Metab. 87 (6) :2629-2634 (2002) .
Other Product Names
14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ
Tested Applications
WB, IHC-P, Flow
Protein ID
52000887
Physical Properties
Liquid

Related Products

CatalogName
63-435YWHAB Antibody
31-026YWHAQ Antibody
31-025YWHAH Antibody
13-734YWHAE Antibody
18-714YWHAQ Antibody
61-614YWHAG Antibody
13-518YWHAB Antibody
63-434YWHAB Antibody
23-787YWHAH Antibody
18-250YWHAG Antibody, KO Validated

Alternative Products

CatalogName
70R-21364YWHAZ antibody

Popular Products