PFKFB3 Antibody

CAT: 0223-63-425Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-425Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK) .
NCBI Gene ID
5209
Swiss Prot
Q16875
Accession Number
Q16875
Host
Rabbit
Reactivity
Human
Immunogen
This PFKFB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-484 amino acids from the C-terminal region of human PFKFB3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Symbol
PFKFB3
NCBI Official Name
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
NCBI Organism
Homo sapiens
Background Reference 01
Navarro-Sabate, A., et al., Gene 264 (1) :131-138 (2001) . Chesney, J., et al., Proc. Natl. Acad. Sci. U.S.A. 96 (6) :3047-3052 (1999) . Sakakibara, R., et al., J. Biochem. 122 (1) :122-128 (1997) . Hamilton, J.A., et al., Mol. Endocrinol. 11 (4) :490-502 (1997) . Sakai, A., et al., J. Biochem. 119 (3) :506-511 (1996) .
Other Product Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, 6PF-2-K/Fru-2,6-P2ase 3, PFK/FBPase 3, 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme, Renal carcinoma antigen NY-REN-56, iPFK-2, 6-phosphofructo-2-kinase, Fructose-2,6-bisphosphatase, PFKFB3
Tested Applications
WB, IHC-P
Protein ID
3023733
Physical Properties
Liquid

Related Products

CatalogName
63-426PFKFB2 Antibody
42-201PFKFB2 Antibody
23-840PFKFB2 Antibody
63-433PFKFB4 Antibody
63-427PFKFB1 Antibody
63-428PFKFB1 Antibody
42-201PPFKFB2 Peptide
92-350PFKFB1 Recombinant Protein
64-160WAS Antibody
60-596WAS Antibody

Alternative Products

CatalogName
CSB-PA017819GA01HUPFKFB3 Antibody
STJ29025Anti-PFKFB3 antibody
C49656PFKFB3 Conjugated Antibody
MBS8536146-01PFKFB3

Popular Products