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PFKFB2 Antibody

CAT: 0223-23-840Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-23-840Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
NCBI Gene ID
5208
Swiss Prot
O60825
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 446-505 of human PFKFB2 (NP_006203.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 54kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PFKFB2
Positive Control 2
Mouse liver
Positive Control 3
Mouse brain
Positive Control 4
Mouse skeletal muscle
Positive Control 5
Rat liver
NCBI Official Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
NCBI Organism
Homo sapiens
Other Product Names
PFKFB2, fructose-2, 6-bisphosphatase, cardiac isozyme, PFKFB, cardiac, OTTHUMP00000034286, OTTHUMP00000034285, 6PF-2-K/Fru-2, 6-P2ASE heart-type isozyme, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2, PFK-2/FBPase-2, MGC138310, MGC138308, DKFZp781D2217, 6-biphosphatase 2, PFKFB2
Tested Applications
WB
Physical Properties
Liquid

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