WEE1 Antibody

• Background :

  WEE1 is a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

• NCBI Gene ID :

  7465

• Swiss Prot :

  P30291

• Accession Number :

  P30291

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This WEE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-634 amino acids from the C-terminal region of human WEE1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  72 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  WEE1

• NCBI Official Name :

  Wee1-like protein kinase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Kawasaki, H., et al., Oncogene 22 (44) :6839-6844 (2003) .

• Background Reference 02 :

  Hashimoto, O., et al., Mol. Carcinog. 36 (4) :171-182 (2003) .

• Background Reference 03 :

  Yuan, H., et al., J. Virol. 77 (3) :2063-2070 (2003) .

• Background Reference 04 :

  Masaki, T., et al., Hepatology 37 (3) :534-543 (2003) .

• Other Product Names :

  Wee1-like protein kinase, WEE1hu, Wee1A kinase, WEE1

• Tested Applications :

  WB, IHC-P

• Protein ID :

  1351419

• Physical Properties :

  Liquid