WEE1 Antibody

• Background:

  WEE1 is a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

• NCBI Gene ID:

  7465

• Swiss Prot:

  P30291

• Accession Number:

  P30291

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This WEE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-634 amino acids from the C-terminal region of human WEE1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  72 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  WEE1

• NCBI Official Name:

  Wee1-like protein kinase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kawasaki, H., et al., Oncogene 22 (44) :6839-6844 (2003) .

• Background Reference 02:

  Hashimoto, O., et al., Mol. Carcinog. 36 (4) :171-182 (2003) .

• Background Reference 03:

  Yuan, H., et al., J. Virol. 77 (3) :2063-2070 (2003) .

• Background Reference 04:

  Masaki, T., et al., Hepatology 37 (3) :534-543 (2003) .

• Other Product Names:

  Wee1-like protein kinase, WEE1hu, Wee1A kinase, WEE1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  1351419

• Physical Properties:

  Liquid