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PCK2 Antibody

CAT: 0223-63-394Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-394Size:400 µL
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Background
This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.
NCBI Gene ID
5106
Swiss Prot
Q16822
Accession Number
Q16822
Host
Rabbit
Reactivity
Human
Immunogen
This PCK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-54 amino acids from the N-terminal region of human PCK2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
71 kDa
Fragment
Rabbit Ig
Symbol
PCK2
NCBI Official Name
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .
Background Reference 02
Modaressi, S., et al., Biochem. J. 333 (Pt 2), 359-366 (1998) .
Background Reference 03
Modaressi, S., et al., Biochem. J. 315 (Pt 3), 807-814 (1996) .
Other Product Names
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial, PEPCK-M, PCK2, PEPCK2
Tested Applications
WB, IHC-P, IF
Protein ID
290457671
Physical Properties
Liquid

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