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PCK1 Antibody

CAT: 0223-63-393Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-393Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. A mitochondrial isozyme of the encoded protein also has been characterized.
NCBI Gene ID
5105
Swiss Prot
P35558
Accession Number
P35558
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PCK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-70 amino acids from the N-terminal region of human PCK1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
69 kDa
Fragment
Rabbit Ig
Symbol
PCK1
NCBI Official Name
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
NCBI Organism
Homo sapiens
Background Reference 01
Berger, K. et al. PLoS ONE. 4 (3) : e4671 (2009) .
Background Reference 02
Dunten, P., et al., J. Mol. Biol. 316 (2) :257-264 (2002) .
Background Reference 03
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .
Background Reference 04
Deloukas, P., et al., Nature 414 (6866) :865-871 (2001) .
Other Product Names
Phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEPCK-C, PCK1, PEPCK1
Tested Applications
WB, IHC-P
Protein ID
93138710
Physical Properties
Liquid

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