Tiparp Antibody

• Background:

  Poly [ADP-ribose] polymerase using NAD (+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly (ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.

• NCBI Gene ID:

  99929

• Swiss Prot:

  Q8C1B2

• Accession Number:

  Q8C1B2

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Tiparp antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-90 amino acids from the N-terminal region of human Tiparp.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  76 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  Tiparp

• NCBI Official Name:

  TCDD-inducible poly [ADP-ribose] polymerase

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Schmahl, J., Nat. Genet. 39 (1), 52-60 (2007)

• Background Reference 02:

  Ma, Q., Arch. Biochem. Biophys. 404 (2), 309-316 (2002)

• Background Reference 03:

  Ma, Q., Biochem. Biophys. Res. Commun. 289 (2), 499-506 (2001)

• Other Product Names:

  TCDD-inducible poly [ADP-ribose] polymerase, ADP-ribosyltransferase diphtheria toxin-like 14, ARTD14, Tiparp

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid