TIPRL Antibody

• Background:

  TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]) .

• NCBI Gene ID:

  261726

• Swiss Prot:

  O75663

• Accession Number:

  O75663

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TIPRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the C-terminal region of human TIPRL.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  31 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  TIPRL

• NCBI Official Name:

  TIP41-like protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)

• Background Reference 02:

  Cheung, C.L., et al. Hum. Mol. Genet. 18 (4) :679-687 (2009)

• Background Reference 03:

  Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)

• Background Reference 04:

  McConnell, J.L., et al. Oncogene 26 (41) :6021-6030 (2007)

• Other Product Names:

  TIP41-like protein, Putative MAPK-activating protein PM10, Type 2A-interacting protein, TIP, TIPRL

• Tested Applications:

  WB

• Physical Properties:

  Liquid