TIPRL Antibody

• Background :

  TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]) .

• NCBI Gene ID :

  261726

• Swiss Prot :

  O75663

• Accession Number :

  O75663

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This TIPRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the C-terminal region of human TIPRL.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  31 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  TIPRL

• NCBI Official Name :

  TIP41-like protein

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)

• Background Reference 02 :

  Cheung, C.L., et al. Hum. Mol. Genet. 18 (4) :679-687 (2009)

• Background Reference 03 :

  Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)

• Background Reference 04 :

  McConnell, J.L., et al. Oncogene 26 (41) :6021-6030 (2007)

• Other Product Names :

  TIP41-like protein, Putative MAPK-activating protein PM10, Type 2A-interacting protein, TIP, TIPRL

• Tested Applications :

  WB

• Physical Properties :

  Liquid