MERTK Antibody

CAT: 0223-63-251Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-251Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .
NCBI Gene ID
10461
Swiss Prot
Q12866
Accession Number
Q12866
Host
Rabbit
Reactivity
Human
Immunogen
This MERTK antibody is generated from rabbits immunized with a his tag recombinant protein of human MERTK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
110 kDa
Fragment
Rabbit Ig
Symbol
MERTK
NCBI Official Name
Tyrosine-protein kinase Mer
NCBI Organism
Homo sapiens
Background Reference 01
Gal A., Li Y., Thompson D.A., Weir J., Orth U., Jacobson S.G.Nat. Genet. 26:270-271 (2000)
Background Reference 02
Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Nature 434:724-731 (2005)
Other Product Names
Tyrosine-protein kinase Mer, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, MERTK, MER
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
160332297
Physical Properties
Liquid

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