MUC20 Antibody

• Background:

  This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  200958

• Swiss Prot:

  Q8N307

• Accession Number:

  Q8N307

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MUC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human MUC20.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  72 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MUC20

• NCBI Official Name:

  Mucin-20

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Li, G., Am. J. Nephrol. 26 (1), 43-49 (2006)

• Background Reference 02:

  Suzuki, Y., Genome Res. 14 (9), 1711-1718 (2004)

• Background Reference 03:

  Higuchi, T., Mol. Cell. Biol. 24 (17), 7456-7468 (2004)

• Background Reference 04:

  Higuchi, T., J. Biol. Chem. 279 (3), 1968-1979 (2004)

• Other Product Names:

  Mucin-20, MUC-20, MUC20, KIAA1359

• Tested Applications:

  WB, IF

• Protein ID:

  317373415

• Physical Properties:

  Liquid