DSG2 Antibody

CAT: 0223-63-211Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-211Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This protein is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in the DSG2 gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
NCBI Gene ID
1829
Swiss Prot
Q14126
Accession Number
Q14126
Host
Rabbit
Reactivity
Human
Immunogen
This DSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-216 amino acids from the N-terminal region of human DSG2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
122 kDa
Fragment
Rabbit Ig
Symbol
DSG2
NCBI Official Name
Desmoglein-2
NCBI Organism
Homo sapiens
Background Reference 01
Posch, M.G., Mol. Genet. Metab. 95 (1-2), 74-80 (2008)
Background Reference 02
Yu, C.C., J. Formos. Med. Assoc. 107 (7), 548-558 (2008)
Other Product Names
Desmoglein-2, Cadherin family member 5, HDGC, DSG2, CDHF5
Tested Applications
WB, Flow
Protein ID
148876773
Physical Properties
Liquid

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